Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188181 | 0.92 | PSEN1 (0.44) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL13038560 | 0.81 | C5AR1 (0.52) | SMN1; SMN2KEAP1NFE2L2PSEN1PSEN2 | |
| SCHEMBL28877340 | 0.76 | ALDH1A1 (0.50) | CA12CA9SMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL10950386 | 0.74 | KDM4E (0.50) | KEAP1NFE2L2CNR2KDM4ELMNA | |
| SCHEMBL28877353 | 0.74 | KMT2A (0.46) | KMT2ACNR2LMNATAS2R14MAPT | |
| SCHEMBL11779484 | 0.73 | PSEN1 (0.48) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL8346204 | 0.72 | CYP3A4 (0.42) | CA2SMN1; SMN2KEAP1NFE2L2KMT2A | |
| Ditolamide SCHEMBL2110790 | 0.72 | CA9 (0.64) | CA12CA9CA2RAB9ASMN1; SMN2 | |
| SCHEMBL8061758 | 0.72 | PSEN1 (0.46) | KEAP1NFE2L2MEN1KMT2APSEN1 | |
| SCHEMBL8055654 | 0.71 | POLB (0.43) | CA12CA9CA2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168181-A1 | RECYCLABLE METATHESIS CATALYSTS | THE TRUSTEES OF BOSTON COLLEGE | 2016-06-16 | — | — | US | disclosed |
| US-20160168181-A1 | RECYCLABLE METATHESIS CATALYSTS | THE TRUSTEES OF BOSTON COLLEGE | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168181-A1 | RECYCLABLE METATHESIS CATALYSTS | DNMT1, CARM1, ZMYND8 | CA12 2542/4885CA9 3068/4885CA2 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.