Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31220506 | 0.84 | HSD11B1 (0.61) | KMT2AHSD11B1CNR2MAPTTAS2R14 | |
| SCHEMBL25736043 | 0.83 | KMT2A (0.56) | KMT2AHSD11B1TDP1CNR2L3MBTL1 | |
| SCHEMBL28877338 | 0.78 | HSD11B1 (0.59) | KMT2AHSD11B1NR1I2MAPTALDH1A1 | |
| SCHEMBL30038589 | 0.78 | HSD11B1 (0.49) | KMT2AHSD11B1TDP1CNR2L3MBTL1 | |
| SCHEMBL29150781 | 0.75 | KMT2A (0.65) | KMT2AHSD11B1TDP1ESR1MAPT | |
| SCHEMBL11566554 | 0.74 | HSD11B1 (0.45) | KMT2AHSD11B1TDP1CNR2L3MBTL1 | |
| SCHEMBL30309104 | 0.74 | POLB (0.47) | KMT2AHSD11B1TDP1CNR2L3MBTL1 | |
| SCHEMBL17833663 | 0.74 | CA12 (0.43) | KMT2ACNR2MAPTTAS2R14LMNA | |
| SCHEMBL31220539 | 0.73 | HSD11B1 (0.44) | KMT2AHSD11B1CNR2MAPTALDH1A1 | |
| SCHEMBL3899893 | 0.73 | KMT2A (0.56) | KMT2AHSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260135-B | Synthesis method of oxindole compound | 浙江工业大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115260135-A | Synthesis method of oxindole compound | 浙江工业大学 | 2022-11-01 | — | — | CN | disclosed |