SCHEMBL17833829

SCHEMBL17833829

C=c1ccc2c(c1)Oc1cc(O)ccc1C=2c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
ESR2 Q92731 6/20 0.38
ESR1 P03372 6/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
HSP90AB1 P08238 2/20 0.36
BRCA1 P38398 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HSP90AA1 P07900 2/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
YWHAG P61981 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12355823 0.83 LMNA (0.39) MEN1KMT2ATDP1HSD17B10POLB
SCHEMBL12926177 0.82 MEN1 (0.53) ALOX5MEN1KMT2ATDP1HSP90AB1
SCHEMBL15357333 0.79 MEN1 (0.37) MEN1KMT2ATDP1HSP90AB1BRCA1
SCHEMBL12452198 0.77 MAPT (0.34) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL24489855 0.77 MEN1 (0.40) MEN1KMT2ATDP1HSP90AB1BRCA1
SCHEMBL14620246 0.76 HSD17B10 (0.39) ALOX5ESR2MEN1KMT2ATDP1
SCHEMBL12678084 0.75 HSD17B10 (0.38) ALOX5MEN1KMT2ATDP1HSP90AB1
SCHEMBL15483682 0.74 LMNA (0.34) ESR2ESR1TRPA1
SCHEMBL15698125 0.74 CYP19A1 (0.36) MEN1KMT2AMAPTFTOALDH1A1
SCHEMBL16284365 0.73 ESR1 (0.35) ESR2ESR1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160169850-A1 SENSOR MOLECULE UNIV MALTA (MT) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160169850-A1 SENSOR MOLECULE QSOX1, AOX1, SCO2 ALOX5 66/4885ESR2 1349/4885ESR1 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.