Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783392 | 1.00 | LMNA (0.43) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL3132115 | 0.83 | LMNA (0.42) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL3132110 | 0.83 | LMNA (0.42) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL5186509 | 0.81 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL5186521 | 0.81 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL5494077 | 0.81 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MAPTNR1H4EPHX2 | |
| SCHEMBL1782120 | 0.79 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL1782936 | 0.79 | CTBP2 (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL1782938 | 0.79 | CTBP2 (0.38) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL1782119 | 0.79 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118509-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | LMNA 3001/4885SMN1; SMN2 3237/4885MAPT 2689/4885 |
| US-20110118170-A1 | NOVEL 4-ALKYL 1-(3-METHOXY-2-PROPEN-1-YL) BENZENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, OR51E2, CYP1B1 | LMNA 3001/4885SMN1; SMN2 3237/4885MAPT 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.