Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384398 | 0.91 | S1PR1 (0.37) | ITGB3ITGA2BITGB1ITGA4KIFC1 | |
| SCHEMBL17834479 | 0.91 | KIFC1 (0.48) | ITGB3ITGA2BITGB1KIFC1ITGAV | |
| SCHEMBL17834514 | 0.91 | GPR132 (0.44) | ITGB1ITGA4KIFC1GPR34 | |
| SCHEMBL17834623 | 0.90 | KIFC1 (0.45) | KIFC1MMEACECPA1ACE2 | |
| SCHEMBL17834923 | 0.90 | ROCK2 (0.35) | ITGB3ITGA2BITGB1ITGA4KIFC1 | |
| SCHEMBL15037215 | 0.89 | ITGB1 (0.49) | ITGB3ITGA2BITGB1ITGA4KIFC1 | |
| SCHEMBL22449163 | 0.89 | ITGB1 (0.49) | ITGB3ITGA2BITGB1ITGA4KIFC1 | |
| SCHEMBL17834497 | 0.88 | KIFC1 (0.48) | ITGB1ITGA4KIFC1GPR34 | |
| SCHEMBL17834673 | 0.88 | KIFC1 (0.41) | ITGB3ITGA2BITGB1ITGA4KIFC1 | |
| SCHEMBL17834642 | 0.88 | KIFC1 (0.43) | ITGB1ITGA4KIFC1GPR34MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ITGB3 4025/4885ITGA2B 4142/4885ITGB1 3589/4885 |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ITGB3 4025/4885ITGA2B 4142/4885ITGB1 3589/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | ITGB3 3678/4885ITGA2B 4134/4885ITGB1 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.