Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394892 | 0.87 | AKR1B1 (0.47) | AKR1B1KDM4EPOLBMAPTPTGS2 | |
| SCHEMBL508942 | 0.81 | KDM4E (0.50) | THRBKDM4ETHRAPOLBMAPT | |
| SCHEMBL508991 | 0.81 | AKR1B1 (0.47) | AKR1B1KDM4EPTGS2 | |
| SCHEMBL13527353 | 0.79 | PTGDR2 (0.42) | AKR1B1KDM4EPTGDR2POLBMAPT | |
| SCHEMBL1154261 | 0.76 | KDM4E (0.47) | AKR1B1KDM4EPTGDR2MAPTPTGS2 | |
| SCHEMBL20561730 | 0.75 | AKR1B1 (0.44) | THRBAKR1B1KDM4EPTGDR2POLB | |
| SCHEMBL2967307 | 0.75 | KDM4E (0.42) | THRBAKR1B1KDM4EPTGDR2POLB | |
| SCHEMBL29188157 | 0.75 | KDM4E (0.46) | THRBAKR1B1KDM4ETHRAPOLB | |
| SCHEMBL24433225 | 0.73 | KDM4E (0.34) | THRBKDM4ETHRAPOLBMAPT | |
| Hydrochloric Acid SCHEMBL26685499 | 0.73 | KDM4E (0.41) | THRBAKR1B1KDM4EPTGDR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | PNPO, PDXK, PRDX1 | THRB 1459/4885AKR1B1 292/4885KDM4E 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.