Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394892 | 0.90 | AKR1B1 (0.47) | AKR1B1PTGS2KDM4E | |
| SCHEMBL5191843 | 0.86 | AKR1B1 (0.61) | AKR1B1PTGS2KDM4E | |
| SCHEMBL918915 | 0.85 | P2RX7 (0.43) | P2RX7KDM4E | |
| SCHEMBL510475 | 0.85 | MAPT (0.50) | AKR1B1PTGS2KDM4E | |
| SCHEMBL13527353 | 0.81 | PTGDR2 (0.42) | AKR1B1PTGS2KDM4E | |
| SCHEMBL1783474 | 0.81 | THRB (0.40) | AKR1B1PTGS2KDM4E | |
| SCHEMBL20561730 | 0.81 | AKR1B1 (0.44) | AKR1B1PTGS2KDM4E | |
| SCHEMBL6307051 | 0.80 | MAPT (0.50) | P2RX7 | |
| SCHEMBL509488 | 0.79 | PTGDR2 (0.46) | AKR1B1PTGS2P2RX7KDM4E | |
| SCHEMBL1154261 | 0.79 | KDM4E (0.47) | AKR1B1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AG (DE) | 2005-07-28 | — | — | US | claimed |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | LIEB FOLKER (DE) | 2003-10-23 | — | — | US | claimed |
| EP-0825982-B1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-11-27 | — | — | EP | claimed |
| EP-0825982-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-03-04 | — | — | EP | claimed |
| WO-1996035664-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | claimed |
| EP-2734526-B1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-06 | — | — | EP | disclosed |
| US-9221832-B2 | Heterocyclic amide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-12-29 | — | — | US | disclosed |
| US-20140163035-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-06-12 | — | — | US | disclosed |
| EP-2734526-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2014-05-28 | — | — | EP | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8470738-B2 | Pyridazinone compound and herbicide containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| WO-2013014587-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-01-31 | — | — | WO | disclosed |
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AG (DE) | 2005-07-28 | — | — | US | disclosed |
| US-6858741-B2 | Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-22 | — | — | US | disclosed |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | LIEB FOLKER (DE) | 2003-10-23 | — | — | US | disclosed |
| EP-0825982-B1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6380246-B1 | FOR COMBATING PESTS AND WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
| US-6316486-B1 | FOR COMBATING PESTS AND WEED | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
| EP-0825982-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996035664-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | DDT, CYP8B1, PAOX | AKR1B1 21/4885PTGS2 739/4885P2RX7 2368/4885 |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | CYP2E1, CYP8B1, CYP24A1 | AKR1B1 43/4885PTGS2 558/4885P2RX7 2530/4885 |
| US-20140163035-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | P2RX7, P2RX3, P2RX1 | AKR1B1 834/4885PTGS2 1489/4885P2RX7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.