⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762328 | 0.81 | TSHR (0.52) | — | |
| SCHEMBL16386315 | 0.72 | — | — | |
| SCHEMBL13756317 | 0.68 | — | — | |
| SCHEMBL14821793 | 0.68 | LMNA (0.40) | — | |
| SCHEMBL23948566 | 0.64 | ALDH1A1 (0.38) | — | |
| SCHEMBL23603986 | 0.64 | ADORA3 (0.35) | — | |
| Succinic Acid SCHEMBL3628497 | 0.62 | EGLN1 (0.82) | — | |
| Succinic Acid SCHEMBL30575212 | 0.62 | EGLN1 (0.82) | — | |
| Succinic Acid SCHEMBL27584447 | 0.62 | EGLN1 (0.82) | — | |
| SCHEMBL22769188 | 0.61 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | UNIV SHANGHAI TECHNOLOGY (CN) | 2022-01-20 | — | — | US | disclosed |
| WO-2020154673-A1 | BIS(DIAZIRINE) DERIVATIVES AS PHOTO-CROSSSLINKER FOR TREATING CORNEAL ECTATIC DISORDERS | AVEDRO, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| US-10017520-B2 | Myc modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |