SCHEMBL17835374

SCHEMBL17835374

ClC(Cl)O[SiH2]c1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.39
CYP2A6 P11509 4/20 0.39
PAX8 Q06710 1/20 0.36
ALDH1A1 P00352 7/20 0.36
HSD17B10 Q99714 5/20 0.36
TDP1 Q9NUW8 3/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 2/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 3/20 0.34
CYP3A4 P08684 2/20 0.34
KEAP1 Q14145 1/20 0.34
HPRT1 P00492 1/20 0.33
ABCB11 O95342 1/20 0.32
NR3C1 P04150 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ALOX15 P16050 1/20 0.32
ADRA2C P18825 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487309 0.81 KDM4E (0.39) CYP1A2CYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL15067861 0.78 SLC6A4 (0.37) CYP1A2CYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL15302524 0.77 ALDH1A1 (0.32) CYP1A2CYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL22661061 0.77 ADRA2A (0.36) CYP1A2CYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL22661044 0.76 AOC3 (0.36) CYP1A2CYP2A6ALDH1A1CYP2C19HPGD
SCHEMBL28460020 0.75 HPGD (0.34) CYP2A6ALDH1A1TSHRHPGDKDM4E
SCHEMBL15302884 0.74 ALDH1A1 (0.43) CYP1A2CYP2A6PAX8ALDH1A1HSD17B10
SCHEMBL15302195 0.73 MEN1 (0.33) CYP1A2ALDH1A1TDP1CYP2C19CYP2C9
SCHEMBL15066596 0.73 UGT2B7 (0.39) CYP1A2CYP2A6ALDH1A1HSD17B10TDP1
SCHEMBL28446983 0.72 NR2E1 (0.33) TDP1ADRA2AADRA2CHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034543-B1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORP (JP) 2021-03-31 EP disclosed
US-9670326-B2 Curable composition, curing product, and method for using curable composition LINTEC CORPORATION (JP) 2017-06-06 US disclosed
US-9540490-B2 Curable composition, curing product, and method for using curable composition LINTEC CORPORATION (JP) 2017-01-10 US disclosed
US-20160229961-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORPORATION (JP) 2016-08-11 US disclosed
US-20160208054-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORPORATION (JP) 2016-07-21 US disclosed
EP-3034543-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION Lintec Corporation (JP) 2016-06-22 EP disclosed
EP-3034560-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION Lintec Corporation (JP) 2016-06-22 EP disclosed