Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | RAD52 | P43351 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720723 | 0.96 | HSD17B10 (0.68) | HSD17B10RAD52POLBSMYD2SLC6A2 | |
| SCHEMBL5482155 | 0.90 | SMYD2 (0.68) | HSD17B10POLBSMYD2MAPTMEN1 | |
| SCHEMBL10192030 | 0.88 | ALDH1A1 (0.70) | HSD17B10POLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL12760681 | 0.86 | MAPT (0.64) | RAD52POLBSMYD2LMNAMAPT | |
| SCHEMBL16227646 | 0.85 | ALDH1A1 (0.69) | LMNAMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL104345 | 0.84 | LMNA (0.67) | RAD52POLBSMYD2SLC6A2SLC6A4 | |
| SCHEMBL178534 | 0.84 | KMT2A (0.71) | RAD52SLC6A2SLC6A4LMNAMAPT | |
| SCHEMBL280088 | 0.83 | HSD17B10 (0.72) | HSD17B10RAD52POLBSMYD2ALDH1A1 | |
| SCHEMBL842621 | 0.82 | HSD17B10 (0.70) | HSD17B10POLBSMYD2SMN1; SMN2MEN1 | |
| SCHEMBL13778294 | 0.81 | PHF13 (0.56) | RAD52POLBSLC6A2SLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059162-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059162-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | NR0B1, GRK7, NR5A2 | HSD17B10 1704/4885RAD52 1823/4885POLB 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.