Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 5/20 | 0.33 |
| ▸ | THRA | P10827 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079515 | 0.94 | HDAC1 (0.38) | TDP1ALDH1A1USP2HPGDHDAC1 | |
| SCHEMBL1004080 | 0.85 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11328438 | 0.84 | TDP1 (0.48) | TDP1ALDH1A1USP2HPGDHDAC1 | |
| SCHEMBL12989712 | 0.82 | TDP1 (0.52) | TDP1ALDH1A1USP2HPGDHDAC1 | |
| SCHEMBL11336193 | 0.82 | TDP1 (0.52) | TDP1ALDH1A1USP2HPGDHDAC1 | |
| SCHEMBL11803736 | 0.82 | MAOA (0.40) | ALDH1A1LMNA | |
| SCHEMBL11690401 | 0.79 | SIGMAR1 (0.41) | ALDH1A1LMNATSHR | |
| SCHEMBL27583870 | 0.79 | IGF1R (0.31) | — | |
| SCHEMBL648362 | 0.78 | MAOA (0.52) | TDP1ALDH1A1USP2HPGDHDAC1 | |
| SCHEMBL29819537 | 0.77 | HDAC1 (0.43) | TDP1ALDH1A1USP2HPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263709-B2 | Crystal nucleating agents, crystalline polymer composition, methods of manufacture thereof, and articles thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110118415-A1 | CRYSTAL NUCLEATING AGENTS, CRYSTALLINE POLYMER COMPOSITION, METHODS OF MANUFACTURE THEREOF, AND ARTICLES THEREOF | THE UNIVERSITY OF MASSACHUSETTS (US) | 2011-05-19 | — | — | US | disclosed |
| US-7723450-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2007-11-08 | — | — | US | disclosed |
| CN-1964998-A | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2007-05-16 | — | — | CN | disclosed |
| EP-1761571-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM., CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005118654-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | ZYX, ZC3HAV1L, ZKSCAN2 | TDP1 4607/4885ALDH1A1 2307/4885USP2 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.