Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783552 | 0.94 | TRPA1 (0.46) | CA2TRPA1DDAH1GAPDHMAPT | |
| SCHEMBL1785240 | 0.92 | TRPA1 (0.44) | CA2TRPA1DDAH1GAPDHMAPT | |
| SCHEMBL1786619 | 0.86 | TSHR (0.35) | TSHRTRPA1DDAH1GAPDHMAPT | |
| SCHEMBL1786930 | 0.80 | GAPDH (0.46) | TSHRSMN1; SMN2CA2MAPK1TRPA1 | |
| SCHEMBL1786928 | 0.80 | GAPDH (0.46) | TSHRSMN1; SMN2CA2MAPK1TRPA1 | |
| SCHEMBL1784149 | 0.77 | — | — | |
| SCHEMBL27613407 | 0.76 | TSHR (0.46) | TSHRSMN1; SMN2CA2MAPK1TRPA1 | |
| SCHEMBL574359 | 0.74 | TSHR (0.52) | TSHRCA2MAPK1CA1FDPS | |
| SCHEMBL2843015 | 0.72 | CA2 (0.43) | TSHRCA2MAPK1MAPTCA1 | |
| SCHEMBL8533665 | 0.72 | CA2 (0.39) | TSHRCA2MAPK1CA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-0274075-B1 | POLYVINYL ACETAL, LIGHT-SENSITIVE COMPOSITION CONTAINING IT AND REPRODUCTION MATERIAL MADE THEREFROM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-26 | — | — | EP | disclosed |
| US-4940646-A | Polyvinyl acetal with hydroxy aliphatic acetal groups useful in photosensitive negative working compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-10 | — | — | US | disclosed |
| EP-0274075-A2 | Polyvinyl acetal, light-sensitive composition containing it and reproduction material made therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | TSHR 2479/4885SMN1; SMN2 2144/4885CA2 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.