Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836998 | 0.91 | TDP1 (0.42) | TDP1TP53TPMTTTRHMGB1 | |
| SCHEMBL17836974 | 0.85 | ESR1 (0.55) | TDP1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17836991 | 0.84 | SMN1; SMN2 (0.36) | TDP1TP53KMT2A | |
| SCHEMBL31491424 | 0.79 | TP53 (0.58) | TDP1TP53TPMTTTRHMGB1 | |
| SCHEMBL18281063 | 0.74 | TP53 (0.45) | TDP1TP53TPMTTTRHMGB1 | |
| SCHEMBL1043966 | 0.74 | TP53 (0.45) | TDP1TP53TPMTTTRHPGD | |
| SCHEMBL19730670 | 0.73 | TP53 (0.50) | TP53TPMTTTRHMGB1HPGD | |
| SCHEMBL30211325 | 0.71 | TP53 (0.58) | TP53TPMTTTRHMGB1HPGD | |
| SCHEMBL607243 | 0.71 | TP53 (0.58) | TP53TPMTTTRHMGB1HPGD | |
| SCHEMBL10942697 | 0.71 | TP53 (0.53) | TDP1TP53TPMTTTRHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10087285-B2 | Biocompatible iodinated diphenol monomers and polymers | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3237487-A2 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | Rutgers, the State University of New Jersey (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016103224-A2 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-06-30 | — | — | WO | disclosed |
| US-20160177028-A1 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10087285-B2 | Biocompatible iodinated diphenol monomers and polymers | DDT, HPGDS, PTGDR | TDP1 2821/4885TP53 454/4885TPMT 2599/4885 |
| US-20160177028-A1 | BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS | DDT, HPGDS, PTGDR | TDP1 2821/4885TP53 454/4885TPMT 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.