SCHEMBL17838799

SCHEMBL17838799

O=S(=O)(CCCI)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.52
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
HDAC1 Q13547 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
HSD11B1 P28845 5/20 0.48
MMP3 P08254 2/20 0.47
MMP8 P22894 2/20 0.47
MMP13 P45452 2/20 0.47
MMP1 P03956 1/20 0.47
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3927298 0.94 KEAP1 (0.54) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL6757831 0.86 PSIP1 (0.56) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL576918 0.86 KEAP1 (0.63) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL10629823 0.86 PSIP1 (0.61) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL7295821 0.84 PSIP1 (0.54) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL10626503 0.84 HDAC1 (0.65) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL7299100 0.83 KEAP1 (0.56) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL777601 0.81 PSIP1 (0.67) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL7298807 0.81 HDAC1 (0.57) PSIP1KEAP1NFE2L2HDAC1HDAC8
SCHEMBL7295494 0.81 HDAC1 (0.57) PSIP1KEAP1NFE2L2HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181592-B1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP GOODYEAR TIRE & RUBBER (US) 2018-08-22 EP disclosed
US-9994663-B2 Functionalized elastomer containing a sulfur group THE GOODYEAR TIRE & RUBBER COMPANY (US) 2018-06-12 US disclosed
US-9994663-B2 Functionalized elastomer containing a sulfur group THE GOODYEAR TIRE & RUBBER COMPANY (US) 2018-06-12 US disclosed
US-9994663-B2 Functionalized elastomer containing a sulfur group THE GOODYEAR TIRE & RUBBER COMPANY (US) 2018-06-12 US disclosed
EP-3181592-A1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP The Goodyear Tire & Rubber Company (US) 2017-06-21 EP disclosed
EP-3181592-A1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP The Goodyear Tire & Rubber Company (US) 2017-06-21 EP disclosed
EP-3159347-A1 METHOD FOR PRODUCING SULFONYL-BOND-CONTAINING SILANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2017-04-26 EP disclosed
US-20160177010-A1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2016-06-23 US disclosed
US-20160177010-A1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2016-06-23 US disclosed
US-20160177010-A1 FUNCTIONALIZED ELASTOMER CONTAINING A SULFUR GROUP MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2016-06-23 US disclosed