SCHEMBL576918

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10626503	0.97	HDAC1 (0.65)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL10629823	0.95	PSIP1 (0.61)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL7299100	0.91	KEAP1 (0.56)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL777601	0.89	PSIP1 (0.67)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL17266530	0.89	KEAP1 (0.54)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL6096865	0.89	KEAP1 (0.54)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL7295494	0.89	HDAC1 (0.57)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL15186463	0.89	HDAC1 (0.57)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL3917294	0.89	CA2 (0.67)	KEAP1NFE2L2HDAC1HDAC8HDAC2
	SCHEMBL2445501	0.89	PSIP1 (0.61)	KEAP1NFE2L2HDAC1HDAC8HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.