Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GFER | P55789 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446440 | 0.90 | ALDH1A1 (0.72) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL1047477 | 0.88 | MAPT (0.57) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL16764224 | 0.86 | MAPT (0.57) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL5743020 | 0.84 | L3MBTL1 (0.58) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL1045480 | 0.84 | L3MBTL1 (0.58) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL1044237 | 0.83 | MAPT (0.58) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL16195572 | 0.81 | MAPT (0.50) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL22466041 | 0.81 | L3MBTL1 (0.59) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL156523 | 0.80 | MAPT (0.68) | ALDH1A1MAPTGFERL3MBTL1KMT2A | |
| SCHEMBL3035197 | 0.78 | LGMN (0.60) | ALDH1A1MAPTGFERL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556148-B2 | N-cyanomethylamides as inhibitors of janus kinase | CADILA HEALTHCARE LIMITED (IN) | 2017-01-31 | — | — | US | disclosed |
| US-20160176849-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | CADILA HEALTHCARE LIMITED (IN) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176849-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | JAK1, JAK3, JAK2 | ALDH1A1 2346/4885MAPT 3232/4885GFER 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.