Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844164 | 0.76 | KAT2B (0.38) | PIM1PIM3 | |
| SCHEMBL1998190 | 0.73 | NR1H2 (0.43) | DDB1CRBNCCR6 | |
| SCHEMBL5316660 | 0.73 | METAP1 (0.49) | — | |
| SCHEMBL17844153 | 0.73 | MAPK8 (0.41) | — | |
| SCHEMBL17844250 | 0.70 | KAT2B (0.41) | — | |
| SCHEMBL17844240 | 0.69 | CHRM4 (0.39) | — | |
| SCHEMBL17844175 | 0.67 | CA12 (0.38) | — | |
| SCHEMBL3551960 | 0.66 | BRD4 (0.39) | — | |
| SCHEMBL17844088 | 0.65 | KDM4E (0.40) | — | |
| SCHEMBL1997801 | 0.65 | TEAD1 (0.42) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |