Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 4/20 | 0.38 |
| ▸ | SKP1 | P63208 | 4/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844219 | 0.90 | CKS1B (0.38) | GPR119CKS1BSKP1SKP2HRH3 | |
| SCHEMBL17844177 | 0.89 | JAK2 (0.46) | GPR119SMOJAK2JAK3 | |
| SCHEMBL5260026 | 0.89 | GPR119 (0.38) | GPR119CKS1BSKP1SKP2KCNH2 | |
| SCHEMBL17844250 | 0.87 | KAT2B (0.41) | GPR119CKS1BSKP1SKP2HRH3 | |
| SCHEMBL3546550 | 0.82 | LMNA (0.42) | CKS1BSKP1SKP2LCAT | |
| SCHEMBL17844145 | 0.81 | HRH3 (0.38) | CKS1BSKP1SKP2HRH3LCAT | |
| SCHEMBL17844172 | 0.81 | GLS (0.43) | KCNH2 | |
| SCHEMBL17844162 | 0.81 | HRH3 (0.41) | CHRM4HRH3KCNH2LCAT | |
| SCHEMBL17844164 | 0.80 | KAT2B (0.38) | — | |
| SCHEMBL5316660 | 0.77 | METAP1 (0.49) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |