Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844237 | 0.89 | PTPN1 (0.41) | JAK1MAPTMAPK1POLBHSD17B10 | |
| SCHEMBL17844179 | 0.87 | MEN1 (0.47) | JAK1EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL17844211 | 0.84 | L3MBTL1 (0.45) | MEN1KMT2ATACR3ALDH1A1L3MBTL1 | |
| SCHEMBL17844164 | 0.84 | KAT2B (0.38) | MAPK9MAPK1POLB | |
| SCHEMBL17844268 | 0.79 | POLB (0.47) | KMT2AMAPTALDH1A1RAB9APOLB | |
| SCHEMBL17844250 | 0.77 | KAT2B (0.41) | MAPTNPC1ALDH1A1MAPK1HTT | |
| SCHEMBL17844219 | 0.75 | CKS1B (0.38) | — | |
| SCHEMBL17844177 | 0.74 | JAK2 (0.46) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL5260026 | 0.74 | GPR119 (0.38) | — | |
| SCHEMBL17844240 | 0.74 | CHRM4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |