Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844088 | 0.82 | KDM4E (0.40) | CA12CA9CA2ATMPLK1 | |
| SCHEMBL3551960 | 0.80 | BRD4 (0.39) | ATMMEN1KMT2AGAAMAPT | |
| SCHEMBL17844227 | 0.77 | POLB (0.39) | CA12CA9CA2MEN1KMT2A | |
| SCHEMBL5223414 | 0.76 | CA12 (0.40) | CA12CA9CA2MEN1KMT2A | |
| SCHEMBL17844110 | 0.75 | MAOA (0.40) | MEN1KMT2APOLB | |
| SCHEMBL3653144 | 0.75 | SMN1; SMN2 (0.36) | CA12CA9CA2 | |
| SCHEMBL17844164 | 0.75 | KAT2B (0.38) | CA12CA9CA2POLB | |
| SCHEMBL17844119 | 0.74 | TAAR1 (0.40) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL17844139 | 0.73 | FDPS (0.36) | ATMMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17844206 | 0.71 | NPC1 (0.41) | MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |