Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844388 | 0.84 | THRA (0.42) | TTRALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4841298 | 0.81 | LMNA (0.47) | TTRUSP2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4841289 | 0.79 | BCL9 (0.47) | TTRUSP2ALDH1A1KDM4EMAPT | |
| SCHEMBL29524525 | 0.78 | RAB9A (0.47) | TTRALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL15295180 | 0.78 | PDE4D (0.53) | TTRKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL25314928 | 0.78 | RAB9A (0.47) | TTRALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL25315062 | 0.78 | MAPT (0.50) | TTRALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL16702181 | 0.78 | SCN8A (0.47) | ALDH1A1KDM4EATML3MBTL1RAB9A | |
| SCHEMBL13125223 | 0.76 | EGFR (0.50) | TTRUSP2ALDH1A1KDM4EMAPT | |
| SCHEMBL12365605 | 0.76 | LMNA (0.49) | TTRALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233847-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex Suisse SA (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098005-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2016-06-23 | — | — | WO | disclosed |