Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784472 | 0.85 | HTR7 (0.43) | HTR7PDCD1CD274FOLH1USP7 | |
| SCHEMBL9806251 | 0.80 | PDCD1 (0.47) | HTR7PDCD1CD274FOLH1USP7 | |
| SCHEMBL29534571 | 0.76 | HTR7 (0.47) | HTR7DPP4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6893252 | 0.76 | HTR7 (0.47) | HTR7DPP4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4629930 | 0.76 | PDCD1 (0.40) | HTR7PDCD1CD274FOLH1USP7 | |
| SCHEMBL1785047 | 0.76 | PDCD1 (0.48) | HTR7PDCD1CD274ALDH1A1HPGD | |
| SCHEMBL9717406 | 0.75 | PDCD1 (0.47) | HTR7PDCD1CD274DPP4SLC5A2 | |
| SCHEMBL29699190 | 0.75 | PDCD1 (0.47) | HTR7PDCD1CD274DPP4SLC5A2 | |
| SCHEMBL8372953 | 0.73 | GABRA1 (0.41) | — | |
| SCHEMBL473270 | 0.73 | PDCD1 (0.50) | PDCD1CD274FOLH1DPP4SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323975-B1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | SI GROUP INC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-9796939-B2 | Multi-ring antioxidants with antiwear properties | SI GROUP, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20140038871-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-8580718-B2 | Multi-ring antioxidants with antiwear properties | ALBERMARLE CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
| EP-2323975-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | Albemarle Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010011523-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | GSR, CBR1, SOD1 | HTR7 2331/4885PDCD1 1999/4885CD274 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.