SCHEMBL17845133

SCHEMBL17845133

CCCC(O)OC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.37
HSPD1 P10809 1/20 0.36
BLM P54132 1/20 0.36
HSPE1 P61604 1/20 0.36
KDM4E B2RXH2 3/20 0.35
LMNA P02545 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
ACLY P53396 2/20 0.33
CPT2 P23786 1/20 0.33
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC13A5 Q86YT5 5/20 0.32
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10793318 0.89 HSPD1 (0.46) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL17845117 0.88 HSPD1 (0.48) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL1924843 0.88 HSPD1 (0.48) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL17845100 0.88 HSPD1 (0.48) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL17845122 0.88 HSPD1 (0.48) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL9258278 0.87 ALDH1A1 (0.52) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL4339036 0.84 ALDH1A1 (0.48) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL4741354 0.83 ALDH1A1 (0.47) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL23168543 0.81 HSPD1 (0.42) ALDH1A1MAPTHSPD1BLMHSPE1
SCHEMBL22541895 0.81 ALDH1A1 (0.48) ALDH1A1MAPTKDM4ELMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024020566-A2 BALLOON DELIVERY SYSTEM FOR THE IMPLANT DEPLOYMENT NORTHWESTERN UNIVERSITY (US) 2024-01-25 WO disclosed
US-20240009357-A1 3D PRINTING OF BIOMEDICAL IMPLANTS NORTHWESTERN UNIVERSITY 2024-01-11 US disclosed
US-11565026-B2 3D printing of biomedical implants NORTHWESTERN UNIVERSITY (US) 2023-01-31 US disclosed
US-20210346576-A1 3D PRINTING OF BIOMEDICAL IMPLANTS NORTHWESTERN UNIVERSITY 2021-11-11 US disclosed
US-20200179574-A1 3D PRINTING OF BIOMEDICAL IMPLANTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2020-06-11 US disclosed
US-10561761-B2 Polymer metal-organic framework composites NORTHWESTERN UNIVERSITY (US) 2020-02-18 US disclosed
US-10463745-B2 Materials for tissue regeneration NORTHWESTERN UNIVERSITY (US) 2019-11-05 US disclosed
US-10463769-B2 Thromboresistant-anticoagulant extracellular matrix NORTHWESTERN UNIVERSITY (US) 2019-11-05 US disclosed
US-20180236122-A1 POLYMER METAL-ORGANIC FRAMEWORK COMPOSITES NORTHWESTERN UNIVERSITY 2018-08-23 US disclosed
US-20180125990-A1 MATERIALS FOR TISSUE REGENERATION NORTHWESTERN UNIVERSITY 2018-05-10 US disclosed
US-20180117219-A1 3D PRINTING OF BIOMEDICAL IMPLANTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2018-05-03 US disclosed
EP-3294312-A1 MATERIALS FOR TISSUE REGENERATION Northwestern University (US) 2018-03-21 EP disclosed
US-20170360992-A1 THROMBORESISTANT-ANTICOAGULANT EXTRACELLULAR MATRIX NORTHWESTERN UNIVERSITY 2017-12-21 US disclosed
WO-2016183277-A1 MATERIALS FOR TISSUE REGENERATION NORTHWESTERN UNIVERSITY (US) 2016-11-17 WO disclosed
WO-2016176444-A1 3D PRINTING OF BIOMEDICAL IMPLANTS NORTHWESTERN UNIVERSITY (US) 2016-11-03 WO disclosed
WO-2016100846-A1 THROMBORESISTANT-ANTICOAGULANT EXTRACELLULAR MATRIX NORTHWESTERN UNIVERSITY (US) 2016-06-23 WO disclosed
WO-2016100847-A2 POLYMER METAL-ORGANIC FRAMEWORK COMPOSITES NORTHWESTERN UNIVERSITY (US) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10561761-B2 Polymer metal-organic framework composites PARN, PUF60, PPIF ALDH1A1 1015/4885MAPT 983/4885HSPD1 1731/4885
US-20180236122-A1 POLYMER METAL-ORGANIC FRAMEWORK COMPOSITES PARN, PUF60, PPIF ALDH1A1 1015/4885MAPT 983/4885HSPD1 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.