Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17056174 | 0.89 | PTGS2 (0.33) | TRPV4RAPGEF4L3MBTL1POLBGAA | |
| SCHEMBL14902115 | 0.87 | RAPGEF4 (0.35) | TRPV4RAPGEF4L3MBTL1POLBGAA | |
| SCHEMBL9339232 | 0.84 | RAPGEF4 (0.41) | TRPV4RAPGEF4L3MBTL1POLBGAA | |
| SCHEMBL16784556 | 0.83 | TRPV4 (0.38) | TRPV4SMN1; SMN2 | |
| SCHEMBL1094769 | 0.83 | TRPV4 (0.32) | TRPV4RAPGEF4POLBGAASMN1; SMN2 | |
| SCHEMBL17203486 | 0.82 | POLB (0.40) | TRPV4L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL17203518 | 0.82 | POLB (0.37) | TRPV4L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL26512771 | 0.82 | CA1 (0.31) | TRPV4 | |
| SCHEMBL1169702 | 0.79 | CA12 (0.38) | TRPV4L3MBTL1 | |
| SCHEMBL19613829 | 0.78 | POLB (0.37) | TRPV4L3MBTL1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202493-B1 | PROCESS FOR THE PREPARATION OF 5-FLUOROTOLUENE-2,4-DISULFOCHLORIDE | BAYER AG (DE) | 1988-08-24 | — | — | EP | claimed |
| US-4740333-A | Process for the preparation of 5-fluorotoluene-2,4-disulphochloride | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | claimed |
| US-5723613-A | Process for the free-radical chlorination or bromination of methyl aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| US-4740333-A | Process for the preparation of 5-fluorotoluene-2,4-disulphochloride | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4740333-A | Process for the preparation of 5-fluorotoluene-2,4-disulphochloride | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4740333-A | Process for the preparation of 5-fluorotoluene-2,4-disulphochloride | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| EP-0202493-A1 | Process for the preparation of 5-fluorotoluene-2,4-disulfochloride | BAYER AG (DE) | 1986-11-26 | — | — | EP | disclosed |