Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.37 |
| ▸ | GLRB | P48167 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845555 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2KMT2AALDH1A1ALOX15 | |
| SCHEMBL17845485 | 0.83 | GAA (0.42) | MAPTSMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL17845784 | 0.82 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL17845726 | 0.80 | KMT2A (0.40) | MAPTSMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL17845502 | 0.77 | MAPT (0.47) | MAPTSMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL17845720 | 0.77 | NPC1 (0.34) | MAPTSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL17845530 | 0.77 | GAA (0.41) | SMN1; SMN2KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL17845700 | 0.73 | GAA (0.46) | MAPTSMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL17845380 | 0.73 | DDB1 (0.40) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1645759 | 0.72 | DRD2 (0.52) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |