Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845604 | 0.83 | GAA (0.47) | GAATSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17845583 | 0.82 | ROCK2 (0.46) | MAPTALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL17845534 | 0.82 | POLB (0.42) | GAAMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17845446 | 0.81 | GAA (0.46) | GAATSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17845485 | 0.80 | GAA (0.42) | GAAMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17845598 | 0.79 | ALDH1A1 (0.36) | GAAMAPTALDH1A1KDM4ETHRB | |
| SCHEMBL17845761 | 0.79 | DDB1 (0.43) | GAAMAPTALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL17845595 | 0.79 | DDB1 (0.43) | SMN1; SMN2NPC1RAB9AHPGDPOLB | |
| SCHEMBL17845380 | 0.78 | DDB1 (0.40) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2563095 | 0.70 | ALDH1A1 (0.55) | GAATSHRMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |