Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845386 | 0.88 | ROCK2 (0.36) | GAAKDM4EP2RX7 | |
| SCHEMBL17845726 | 0.83 | KMT2A (0.40) | GAANPC1RAB9AKMT2AP2RX7 | |
| SCHEMBL17845569 | 0.81 | GAA (0.38) | GAAPOLBNPC1RAB9AKMT2A | |
| SCHEMBL17845720 | 0.81 | NPC1 (0.34) | GAAPOLBNPC1RAB9AKMT2A | |
| SCHEMBL17845502 | 0.81 | MAPT (0.47) | GAAKDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL17845388 | 0.81 | GAA (0.38) | GAAKDM4EPOLBNPC1RAB9A | |
| SCHEMBL17845762 | 0.79 | EPHX2 (0.36) | KMT2AP2RX7EPHX2ALDH1A1TAS1R3 | |
| SCHEMBL17845787 | 0.77 | MAPT (0.40) | GAAKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL17845380 | 0.76 | DDB1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17845595 | 0.73 | DDB1 (0.43) | POLBNPC1RAB9AP2RX7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |