Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21436708 | 0.81 | CHKA (0.50) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| SCHEMBL12464235 | 0.79 | KDM4E (0.55) | KDM4ENPC1RAB9AALDH1A1HTT | |
| SCHEMBL1246751 | 0.75 | RAD52 (0.51) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| SCHEMBL1425997 | 0.74 | KDM4E (0.54) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| SCHEMBL16520752 | 0.74 | KDM4E (0.47) | KDM4ENPC1RAB9AALDH1A1GLA | |
| SCHEMBL1363019 | 0.73 | KDM4E (0.69) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| Bromide SCHEMBL29044184 | 0.73 | KCNA3 (0.46) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| Bromide SCHEMBL1461850 | 0.72 | KDM4E (0.68) | KDM4ENPC1RAB9ALMNACHKA | |
| Bromide SCHEMBL3324489 | 0.72 | CHKA (0.54) | KDM4ENPC1RAB9AMITFALDH1A1 | |
| SCHEMBL10136900 | 0.72 | KDM4E (0.80) | KDM4ENPC1RAB9AMITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975525-B2 | Finely divided, cationic, aqueous polymer dispersions, method for the production thereof, and the use thereof | SOLENIS TECHNOLOGIES, L.P. (US) | 2021-04-13 | — | — | US | disclosed |
| EP-3383929-B1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | SOLENIS TECHNOLOGIES CAYMAN LP (KY) | 2020-11-04 | — | — | EP | disclosed |
| US-20180355558-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2018-12-13 | — | — | US | disclosed |
| EP-3383929-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2018-10-10 | — | — | EP | disclosed |
| US-20170369604-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3233931-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2017093368-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2017-06-08 | — | — | WO | disclosed |
| WO-2016098006-A1 | FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF | BASF SE (DE) | 2016-06-23 | — | — | WO | disclosed |