Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.61 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MYLK | Q15746 | 1/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845900 | 0.89 | ALDH1A1 (0.56) | TMPRSS4P2RX1MEN1KMT2APOLB | |
| SCHEMBL17845909 | 0.88 | P2RX1 (0.58) | TMPRSS4P2RX1P2RX4P2RX7TLR8 | |
| SCHEMBL17859008 | 0.86 | SMN1; SMN2 (0.55) | TMPRSS4P2RX1TLR8LRRK2MEN1 | |
| SCHEMBL17845901 | 0.85 | ALDH1A1 (0.52) | TMPRSS4P2RX1LRRK2MEN1KMT2A | |
| SCHEMBL17858986 | 0.84 | LRRK2 (0.60) | TMPRSS4P2RX1P2RX4P2RX7TLR8 | |
| SCHEMBL17845896 | 0.82 | NPC1 (0.53) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5757242 | 0.82 | ALDH1A1 (0.72) | TMPRSS4P2RX1P2RX4P2RX7TLR8 | |
| SCHEMBL16702757 | 0.81 | P2RX1 (0.67) | TMPRSS4P2RX1P2RX4P2RX7TLR8 | |
| SCHEMBL6102085 | 0.80 | P2RX1 (0.65) | TMPRSS4P2RX1P2RX4P2RX7TLR8 | |
| SCHEMBL29511638 | 0.79 | P2RX1 (0.64) | TMPRSS4P2RX1P2RX4P2RX7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |