Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.58 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | STK39 | Q9UEW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845884 | 0.90 | ALDH1A1 (0.53) | P2RX1TMPRSS4STK39NPC1RAB9A | |
| SCHEMBL17845889 | 0.88 | TMPRSS4 (0.61) | P2RX1P2RX4P2RX7TMPRSS4TLR8 | |
| SCHEMBL17845895 | 0.87 | SMN1; SMN2 (0.52) | TMPRSS4TLR8LRRK2NPC1RAB9A | |
| SCHEMBL17858986 | 0.86 | LRRK2 (0.60) | P2RX1P2RX4P2RX7TMPRSS4TLR8 | |
| SCHEMBL17859065 | 0.86 | ALDH1A1 (0.49) | TMPRSS4LRRK2STK39NPC1RAB9A | |
| SCHEMBL17845911 | 0.84 | STK39 (0.54) | STK39NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16702757 | 0.83 | P2RX1 (0.67) | P2RX1P2RX4P2RX7TMPRSS4TLR8 | |
| SCHEMBL5757242 | 0.79 | ALDH1A1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4TLR8 | |
| SCHEMBL17845899 | 0.79 | ALDH1A1 (0.51) | P2RX1TMPRSS4STK39NPC1RAB9A | |
| SCHEMBL17845904 | 0.78 | SMN1; SMN2 (0.53) | P2RX1P2RX4P2RX7TMPRSS4TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |