Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | STK39 | Q9UEW8 | 2/20 | 0.52 |
| ▸ | PNLIP | P16233 | 7/20 | 0.51 |
| ▸ | PARG | Q86W56 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845900 | 0.90 | ALDH1A1 (0.56) | NPC1PNLIPMAPTKDM4EMEN1 | |
| SCHEMBL17845911 | 0.87 | STK39 (0.54) | NPC1RAB9APTGS1TBXAS1MAPK1 | |
| SCHEMBL17845901 | 0.85 | ALDH1A1 (0.52) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL17858976 | 0.83 | LRRK2 (0.52) | NPC1RAB9APTGS1TBXAS1MAPK1 | |
| SCHEMBL17845889 | 0.82 | TMPRSS4 (0.61) | NPC1RAB9APTGS1MEN1KMT2A | |
| SCHEMBL4913226 | 0.82 | PTGS1 (0.59) | NPC1RAB9APTGS1TBXAS1MAPK1 | |
| SCHEMBL17845899 | 0.77 | ALDH1A1 (0.51) | NPC1RAB9ASTK39PNLIPPARG | |
| SCHEMBL17845884 | 0.77 | ALDH1A1 (0.53) | NPC1RAB9ASTK39PNLIPPARG | |
| SCHEMBL467396 | 0.74 | P2RX1 (0.77) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL4253890 | 0.74 | MEN1 (0.68) | NPC1RAB9APTGS1TBXAS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |