Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17068415 | 0.71 | NOTUM (0.39) | NOTUM | |
| SCHEMBL1019627 | 0.70 | PON1 (0.35) | — | |
| SCHEMBL11397537 | 0.68 | NOTUM (0.50) | NOTUM | |
| SCHEMBL24573784 | 0.67 | NOTUM (0.43) | NOTUM | |
| SCHEMBL18721394 | 0.66 | NOTUM (0.42) | NOTUM | |
| SCHEMBL21768201 | 0.66 | TAAR1 (0.35) | — | |
| SCHEMBL30831841 | 0.66 | TAAR1 (0.35) | — | |
| SCHEMBL24622550 | 0.66 | NOTUM (0.42) | NOTUM | |
| SCHEMBL17845893 | 0.65 | P2RX7 (0.42) | NOTUM | |
| SCHEMBL28035154 | 0.65 | IDO1 (0.40) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233862-A1 | IMIDAZOPYRIDAZINE DERIVATIVES AS 3 INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097347-A1 | IMIDAZOPYRIDAZINE DERIVATIVES AS ΡΙ3Κβ INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-06-23 | — | — | WO | disclosed |