Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537101 | 0.81 | IDO1 (0.43) | IDO1PTPN5CYP3A4CYP2D6HTR2A | |
| SCHEMBL531384 | 0.80 | KLF10 (0.40) | IDO1PTPN5NOTUMCYP3A4CYP2D6 | |
| SCHEMBL532671 | 0.80 | IDO1 (0.40) | IDO1PTPN5CYP3A4CYP2D6HTR2A | |
| SCHEMBL12650016 | 0.80 | ESR1 (0.40) | IDO1PTPN5CYP3A4CYP2D6HTR2A | |
| SCHEMBL5436712 | 0.78 | SLC6A4 (0.43) | IDO1CYP3A4HTR2ASLC6A4KCNH2 | |
| SCHEMBL3188993 | 0.78 | CES2 (0.46) | IDO1PTPN5CYP3A4CYP2D6PDE2A | |
| SCHEMBL16758990 | 0.78 | IDO1 (0.58) | IDO1PTPN5HTR2ASLC6A4KCNH2 | |
| SCHEMBL531423 | 0.77 | PTPN1 (0.38) | IDO1PTPN5CYP3A4CYP2D6HTR2A | |
| SCHEMBL2111621 | 0.76 | IDO1 (0.40) | IDO1NOTUMCYP3A4CYP2D6HTR2A | |
| SCHEMBL3680986 | 0.76 | IDO1 (0.40) | IDO1PTPN5CYP3A4CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958484-B | Oxazolidinone derivative, preparation method and medical application thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |