SCHEMBL178465

SCHEMBL178465

CC[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.60
PLG P00747 1/20 0.60
PLAT P00750 1/20 0.60
ANPEP P15144 1/20 0.47
ENPEP Q07075 1/20 0.47
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
TSHR P16473 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
GABRA4 P48169 1/20 0.42
GABRE P78334 1/20 0.42
PMP22 Q01453 1/20 0.42
GABRA6 Q16445 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14643284 1.00 LMNA (0.60) LMNAPLGPLATANPEPENPEP
SCHEMBL879831 1.00 LMNA (0.60) LMNAPLGPLATANPEPENPEP
Cyclopropane Carboxylic Acid SCHEMBL11636034 1.00 LMNA (0.60) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL8903649 0.98 PLG (0.58) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL11310028 0.98 PLG (0.58) LMNAPLGPLATANPEPENPEP
SCHEMBL2820878 0.93 PLG (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL2820876 0.93 PLG (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL27324720 0.93 LMNA (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL2820881 0.93 PLG (0.54) LMNAPLGPLATANPEPENPEP
SCHEMBL3270204 0.93 PLG (0.54) LMNAPLGPLATANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004071448-A2 SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES TRANSTECH PHARMA INC. (US) 2004-08-26 WO claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
JP-6128196-A None JP disclosed
EP-3990569-B1 NEW POLYMERIZABLE LIQUID CRYSTAL ROLIC TECH AG (CH) 2024-12-04 EP disclosed
CN-118702646-A Novel polymerizable liquid crystal 罗利克技术有限公司 2024-09-27 CN disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
CN-114026078-B Novel polymerizable liquid crystal 罗利克技术有限公司 2024-06-07 CN disclosed
US-20230381177-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE TES PHARMA S.R.L. (IT) 2023-11-30 US disclosed
US-11779578-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-10-10 US disclosed
US-20230303526-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-09-28 US disclosed
US-11702595-B2 Polymerizable liquid crystal Rolic Technologies AG (CH) 2023-07-18 US disclosed
EP-0394906-A2 Liquid crystalline composition MERCK PATENT GmbH (DE) 1990-10-31 EP disclosed
EP-0334911-A1 SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS MERCK PATENT GmbH (DE) 1989-10-04 EP disclosed
WO-1989002884-A1 SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-04-06 WO disclosed
US-4786332-A TOBACCO PRODUCTS GIVAUDAN CORPORATION (US) 1988-11-22 US disclosed
EP-0110362-B1 FRAGRANCE AND FLAVOUR COMPOSITIONS L. GIVAUDAN & CIE Société Anonyme (CH) 1988-04-20 EP disclosed
US-4606925-A Flavoring with alkyl-substituted cyclohexyl and cyclohexenyl carboxylic acids GIVAUDAN CORPORATION (US) 1986-08-19 US disclosed
US-4507290-A CONTRACEPTIVE WORLD HEALTH ORGANIZATION (CH) 1985-03-26 US disclosed
EP-0110362-A2 Fragrance and flavour compositions L. GIVAUDAN & CIE Société Anonyme (CH) 1984-06-13 EP disclosed
US-4357078-A ELECTROOPTICS; DISPLAYING THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1982-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381177-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE ACMSD, GLS, ALDH7A1 LMNA 2315/4885PLG 1751/4885PLAT 1849/4885
US-20230303526-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 LMNA 1656/4885PLG 1441/4885PLAT 1236/4885
US-11779578-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 LMNA 1656/4885PLG 1441/4885PLAT 1236/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R LMNA 3809/4885PLG 2277/4885PLAT 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.