Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880210 | 0.87 | OPRL1 (0.37) | OPRL1OPRM1OPRD1OPRK1KDM1A | |
| SCHEMBL5244042 | 0.78 | OPRL1 (0.39) | OPRL1OPRM1OPRD1OPRK1KDM1A | |
| SCHEMBL337274 | 0.77 | KDM1A (0.40) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL16244242 | 0.71 | GPBAR1 (0.34) | DPP4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8675186 | 0.71 | OPRL1 (0.35) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL24322076 | 0.67 | SLC6A4 (0.38) | OPRL1OPRM1KDM1AMAOBMAOA | |
| SCHEMBL908950 | 0.66 | OPRL1 (0.36) | OPRL1OPRM1CYP2D6SLC6A2SLC6A4 | |
| Benzene SCHEMBL28198346 | 0.66 | OPRL1 (0.36) | OPRL1OPRM1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL4647455 | 0.65 | — | — | |
| SCHEMBL10389478 | 0.65 | DPP4 (0.41) | DPP4OPRL1OPRM1OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246810-B2 | Sprayable cosmetic agent II | HENKEL AG & CO. KGAA (DE) | 2022-02-15 | — | — | US | disclosed |
| EP-3233046-B1 | USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT | OREAL (FR) | 2020-07-29 | — | — | EP | disclosed |
| EP-3600230-A1 | SPRAYABLE COSMETIC AGENT II | Henkel AG & Co. KGaA (DE) | 2020-02-05 | — | — | EP | disclosed |
| US-10548833-B2 | Use of a combination of an associative nonionic polyether polyurethane and a cyclohexanol derivative as a skin refreshing agent | L'OREAL (FR) | 2020-02-04 | — | — | US | disclosed |
| US-20200030196-A1 | SPRAYABLE COSMETIC AGENT II | HENKEL AG & CO. KGAA (DE) | 2020-01-30 | — | — | US | disclosed |
| WO-2018177721-A1 | SPRAYABLE COSMETIC AGENT II | HENKEL AG & CO. KGAA (DE) | 2018-10-04 | — | — | WO | disclosed |
| US-20170367965-A1 | USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT | L'OREAL (FR) | 2017-12-28 | — | — | US | disclosed |
| EP-3233046-A1 | USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT | L'Oréal (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096928-A1 | USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548833-B2 | Use of a combination of an associative nonionic polyether polyurethane and a cyclohexanol derivative as a skin refreshing agent | CUTA, DEGS1, OR51E2 | DPP4 4785/4885OPRL1 484/4885OPRM1 531/4885 |
| US-20170367965-A1 | USE OF A COMBINATION OF AN ASSOCIATIVE NONIONIC POLYETHER POLYURETHANE AND A CYCLOHEXANOL DERIVATIVE AS A SKIN REFRESHING AGENT | CUTA, DEGS1, OR51E2 | DPP4 4785/4885OPRL1 484/4885OPRM1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.