Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 11/20 | 0.34 |
| ▸ | MAOB | P27338 | 11/20 | 0.34 |
| ▸ | MAOA | P21397 | 10/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337274 | 0.92 | KDM1A (0.40) | OPRL1KDM1AMAOBMAOARORC | |
| SCHEMBL4333830 | 0.75 | ESR2 (0.42) | — | |
| SCHEMBL24322076 | 0.73 | SLC6A4 (0.38) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL5244042 | 0.73 | OPRL1 (0.39) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL27488523 | 0.72 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL27630906 | 0.72 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL27772756 | 0.72 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL4753778 | 0.72 | OPRL1 (0.35) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL17847283 | 0.71 | DPP4 (0.37) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL8196759 | 0.70 | GAA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374667-A | Process for the preparation of fluorochlorohydrocarbon-free, low-density polyurethan soft foams and soft elastic polyurethan molding foams and polyisocyanate mixtures modified with urethan groups on diphenylmethane-diisocyanate base | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | claimed |
| EP-0386777-A2 | PS plate for use in making lithographic printing plate requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1990-09-12 | — | — | EP | claimed |
| US-4458007-A | PRINTING PLATES, PHOTORESISTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | claimed |
| CN-101402716-B | Mixed prepolymer of solidifying agent methyl diphenylene diisocyanate and 1,6-hexamethylene diisocyanate and its preparation method | JIANMING ZHOU | 2012-01-11 | — | — | CN | disclosed |
| CN-101402716-A | Mixed prepolymer of solidifying agent methyl diphenylene diisocyanate and 1,6-hexamethylene diisocyanate | JIANMING ZHOU (CN) | 2009-04-08 | — | — | CN | disclosed |
| US-5795633-A | POLYURETHANES, TUBULAR BALLOON FORM | NIPPON ZEON CO., LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0276927-A2 | Storage stable isocyanate prepolymers | POLYOL INTERNATIONAL B.V. (NL) | 1988-08-03 | — | — | EP | disclosed |