Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 20/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 20/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17838891 | 0.83 | CHIT1 (0.58) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838822 | 0.81 | CHIT1 (0.49) | CHIT1CHIAKCNH2 | |
| SCHEMBL17853471 | 0.76 | CHIT1 (0.45) | CHIT1CHIAKCNH2 | |
| SCHEMBL17847361 | 0.73 | CHIT1 (0.49) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838873 | 0.71 | CHIT1 (0.57) | CHIT1CHIAKCNH2 | |
| SCHEMBL16825703 | 0.69 | CHIT1 (0.74) | CHIT1CHIAKCNH2 | |
| Hydrochloric Acid SCHEMBL18129160 | 0.69 | CHIT1 (0.73) | CHIT1CHIAKCNH2 | |
| SCHEMBL17847356 | 0.68 | CHIT1 (0.38) | CHIT1CHIAKCNH2 | |
| SCHEMBL21674338 | 0.68 | CHIT1 (0.64) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838882 | 0.68 | CHIT1 (0.58) | CHIT1CHIAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS S.A. (PL) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016099311-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | WO | disclosed |