SCHEMBL17847463

SCHEMBL17847463

N=C=O.c1ccc(Sc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
KDM4E B2RXH2 1/20 0.47
NSD2 O96028 1/20 0.47
MAPK1 P28482 1/20 0.47
SIRT1 Q96EB6 1/20 0.41
HTR7 P34969 1/20 0.39
ADORA2A P29274 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
BCL2 P10415 1/20 0.35
ALDH1A1 P00352 5/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
BLM P54132 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
LMNA P02545 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550775 0.88 MAPT (0.52) MAPTKDM4ENSD2MAPK1SIRT1
Hydrogen Sulfide SCHEMBL27169707 0.86 MAPT (0.50) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL7737500 0.84 MAPK1 (0.48) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL27880556 0.82 MAPK1 (0.46) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL17065474 0.80 MAPT (0.48) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL9568786 0.80 MAPT (0.48) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL10706537 0.80 MAPT (0.48) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL17292795 0.80 MAPK1 (0.48) MAPTKDM4ENSD2MAPK1SIRT1
Hydrogen Sulfide SCHEMBL28028821 0.79 MAPK1 (0.47) MAPTKDM4ENSD2MAPK1SIRT1
SCHEMBL15418802 0.79 MAPK1 (0.43) MAPTKDM4ENSD2MAPK1SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 EP disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 MAPT 343/4885KDM4E 1395/4885NSD2 59/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 MAPT 343/4885KDM4E 1395/4885NSD2 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.