SCHEMBL17847464

SCHEMBL17847464

O=C=Nc1ccc(-c2ccccc2)c2cccc(Cl)c12

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.38
MAPK14 Q16539 1/20 0.36
FEN1 P39748 1/20 0.35
CYP3A4 P08684 2/20 0.35
PARP1 P09874 1/20 0.33
DYRK1A Q13627 1/20 0.32
CTRC Q99895 2/20 0.32
TYMS P04818 1/20 0.31
CYP1A2 P05177 2/20 0.31
MAP2 P11137 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
CSNK2A1 P68400 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712964 0.82 ALDH1A1 (0.42) CYP3A4PARP1TDP1ALDH1A1HPGD
SCHEMBL17847515 0.82 CYP3A4 (0.42) CYP2A6CYP3A4PARP1CYP1A2TDP1
SCHEMBL19712974 0.82 PARP1 (0.39) CYP3A4PARP1DYRK1ATDP1ALDH1A1
SCHEMBL19713014 0.82 CYP3A4 (0.35) CYP3A4PARP1CYP1A2TDP1ALDH1A1
SCHEMBL9517280 0.81 CYP3A4 (0.39) FEN1CYP3A4PARP1CTRCCYP1A2
SCHEMBL28475406 0.81 CYP3A4 (0.32) CYP3A4TYMS
SCHEMBL21064778 0.80 CYP3A4 (0.40) CYP3A4PARP1CYP1A2TDP1ALDH1A1
SCHEMBL19713010 0.80 GABRA1 (0.45) CYP3A4PARP1CYP1A2TDP1ALDH1A1
SCHEMBL19713022 0.79 CYP3A4 (0.36) CYP3A4PARP1TDP1ALDH1A1HPGD
SCHEMBL19713008 0.76 BCL2 (0.41) CYP3A4HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107223121-B Wet stable holographic media 科思创德国股份有限公司 2020-10-27 CN disclosed
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 EP disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 CYP2A6 2626/4885MAPK14 1119/4885FEN1 1345/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 CYP2A6 2626/4885MAPK14 1119/4885FEN1 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.