Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743146 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL2484846 | 0.81 | BRD4 (0.37) | BRD4ITGB3ITGA2BF2RNPC1 | |
| SCHEMBL4718414 | 0.76 | ITGB3 (0.33) | TLR4ITGB3ITGA2BF2R | |
| SCHEMBL183476 | 0.76 | ITGB3 (0.42) | ITGB3ITGA2BF2R | |
| SCHEMBL2449302 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BF2RNPC1RAB9A | |
| SCHEMBL2127522 | 0.75 | MAPT (0.44) | TLR4NPC1RAB9A | |
| SCHEMBL20954393 | 0.74 | MGAM (0.37) | BRD4 | |
| SCHEMBL2449718 | 0.72 | KMT2A (0.43) | NPC1 | |
| SCHEMBL4772702 | 0.72 | MAPT (0.36) | NPC1RAB9A | |
| SCHEMBL2452276 | 0.72 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233826-A1 | NEW ANTIBACTERIAL COMPOUNDS | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096631-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |