SCHEMBL1784785

SCHEMBL1784785

CCC(C)C(OC)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
DPP4 P27487 6/20 0.33
DPP8 Q6V1X1 5/20 0.33
DPP9 Q86TI2 5/20 0.33
ALDH1A1 P00352 1/20 0.31
MME P08473 2/20 0.31
ACE P12821 2/20 0.31
CPA1 P15085 2/20 0.31
ACE2 Q9BYF1 2/20 0.31
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
DPP7 Q9UHL4 4/20 0.30
FAP Q12884 2/20 0.30
USP2 O75604 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782724 0.86 ALDH1A1 (0.32) SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL13218879 0.85 SLC1A3 (0.30) SLC1A3SLC1A2SLC1A1
SCHEMBL1784275 0.83 PTPN1 (0.33) SLC1A3SLC1A2SLC1A1
SCHEMBL1782784 0.82 METAP1 (0.36) SLC1A3SLC1A2SLC1A1TSHR
SCHEMBL26940431 0.81 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1ALDH1A1MME
SCHEMBL1782816 0.79 SLC1A3 (0.37) SLC1A3SLC1A2SLC1A1ALDH1A1CPA1
SCHEMBL1782165 0.79 CA2 (0.41) SLC1A3SLC1A2SLC1A1ALDH1A1TSHR
SCHEMBL1782615 0.77 SLC1A3 (0.35) SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL1784823 0.77 MME (0.30) MMEACECPA1ACE2
SCHEMBL1784822 0.77 MME (0.30) MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 SLC1A3 4740/4885SLC1A2 4505/4885SLC1A1 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.