SCHEMBL1784867

SCHEMBL1784867

CC(COC(=O)c1ccc(Br)cc1)OC(=O)c1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 2/20 0.53
ALOX12 P18054 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 3/20 0.47
PTPN1 P18031 3/20 0.47
HPGD P15428 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
LMNA P02545 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
PTPN2 P17706 1/20 0.44
PTPN11 Q06124 1/20 0.44
PLA2G1B P04054 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
ADRB2 P07550 3/20 0.43
ADRB1 P08588 3/20 0.43
ADRB3 P13945 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13249515 1.00 KDM4E (0.53) KDM4EALDH1A1ALOX12NPSR1L3MBTL1
Propylene Glycol SCHEMBL4839019 0.93 KDM4E (0.48) KDM4EALDH1A1ALOX12NPSR1L3MBTL1
SCHEMBL9679247 0.88 ALDH1A1 (0.55) KDM4EALDH1A1MAPTHPGDNPC1
SCHEMBL14335316 0.87 ALDH1A1 (0.53) KDM4EALDH1A1ALOX12NPSR1L3MBTL1
SCHEMBL24055108 0.85 MAPT (0.49) ALDH1A1NPSR1MAPTPTPN1LMNA
SCHEMBL1580003 0.85 CA12 (0.62) ALDH1A1MAPTPTPN1NPC1RAB9A
SCHEMBL1784739 0.85 ADRB2 (0.59) ALDH1A1L3MBTL1MAPTPTPN1NPC1
SCHEMBL16217637 0.85 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9ALMNA
SCHEMBL14947115 0.85 ADRB2 (0.59) ALDH1A1L3MBTL1MAPTPTPN1NPC1
SCHEMBL12559135 0.85 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
US-7767388-B2 Method for monitoring the stereoselectivity and relative rate of organic chemical reactions NUTECH VENTURES (US) 2010-08-03 US disclosed
US-7767388-B2 Method for monitoring the stereoselectivity and relative rate of organic chemical reactions NUTECH VENTURES (US) 2010-08-03 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed