Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | PPIB | P23284 | 5/20 | 0.37 |
| ▸ | PPIG | Q13427 | 2/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17262478 | 0.84 | EPHX2 (0.43) | EPHX2 | |
| SCHEMBL21855162 | 0.73 | CASP6 (0.39) | EPHX2 | |
| SCHEMBL27676112 | 0.72 | KMT2A (0.36) | — | |
| SCHEMBL17870745 | 0.71 | CYP2C19 (0.37) | EPHX2EPHX1 | |
| SCHEMBL28387866 | 0.70 | FFAR4 (0.34) | EPHX2PTPN11 | |
| SCHEMBL20766101 | 0.69 | HDAC2 (0.51) | HDAC1HDAC2 | |
| SCHEMBL17262465 | 0.69 | RORC (0.47) | HDAC1 | |
| SCHEMBL17848769 | 0.69 | CASP6 (0.36) | PPIDPPIB | |
| SCHEMBL19641201 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL18154336 | 0.69 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-A1 | DOPAMINE D2 RECEPTOR LIGANDS | The Broad Institute Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100940-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |