Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.80 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848502 | 0.93 | DRD2 (0.76) | DRD2TSHRSIGMAR1 | |
| SCHEMBL17848770 | 0.92 | DRD2 (0.67) | DRD2LTA4HTSHR | |
| SCHEMBL17848571 | 0.89 | DRD2 (1.00) | DRD2LTA4HSIGMAR1PTGS2 | |
| SCHEMBL17848631 | 0.89 | DRD2 (0.90) | DRD2LTA4HSIGMAR1PTGS2 | |
| SCHEMBL17848443 | 0.86 | DRD2 (0.77) | DRD2TSHR | |
| SCHEMBL17848766 | 0.86 | DRD2 (0.65) | DRD2 | |
| SCHEMBL17848429 | 0.86 | DRD2 (0.77) | DRD2TSHRKCNA5 | |
| SCHEMBL17848317 | 0.85 | DRD2 (0.72) | DRD2TSHR | |
| SCHEMBL17848380 | 0.85 | DRD2 (0.80) | DRD2LTA4HSIGMAR1PTGS2 | |
| SCHEMBL17848333 | 0.85 | DRD2 (0.74) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-A1 | DOPAMINE D2 RECEPTOR LIGANDS | The Broad Institute Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100940-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |