SCHEMBL17849623

SCHEMBL17849623

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(-n7c8ccccc8c8ccccc87)cc6)c6ccc(-n7c8ccccc8c8ccccc87)cc6)cc5)cc1c4c23

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC4 P56524 1/20 0.32
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31
TUBA1C Q9BQE3 1/20 0.31
TUBB6 Q9BUF5 1/20 0.31
TUBB2B Q9BVA1 1/20 0.31
TUBB1 Q9H4B7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849628 0.95 KDM4E (0.32) KDM4EATML3MBTL1HDAC4
SCHEMBL17849685 0.92 TSPO (0.35) KDM4EATML3MBTL1
SCHEMBL17849609 0.92 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL17849607 0.92 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL15316879 0.92 KDM4E (0.34) KDM4EATML3MBTL1HDAC4
SCHEMBL15316868 0.90 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL15316856 0.90 KDM4E (0.33) KDM4EATML3MBTL1HDAC4
SCHEMBL17849622 0.87 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL13888805 0.84 LPL (0.34)
SCHEMBL13888806 0.84 LPL (0.34) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed