SCHEMBL17849685

SCHEMBL17849685

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(-c7ccccc7)cc6)c6ccc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)cc6)cc5)cc1c4c23

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.35
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PTGER4 P35408 1/20 0.33
PTGES O14684 1/20 0.33
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849609 0.96 KDM4E (0.34) TSPOKDM4EATML3MBTL1PTGER4
SCHEMBL17849607 0.94 KDM4E (0.34) KDM4EATML3MBTL1PTGER4PTGES
SCHEMBL17849623 0.92 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL17849628 0.91 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL17849622 0.89 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL17849686 0.88 KDM4E (0.33) TSPOKDM4EATML3MBTL1PTGER4
SCHEMBL15316852 0.88 TSPO (0.31) TSPOKDM4EATML3MBTL1PTGER4
SCHEMBL15316856 0.87 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL15316879 0.86 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL23179420 0.85 TSPO (0.34) TSPOKDM4EATML3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed