SCHEMBL17849639

SCHEMBL17849639

CC1(C)c2cccc3ccc4cc(-c5ccc6cc(N(c7ccc(-c8ccccc8)cc7)c7ccc8c(c7)oc7ccccc78)ccc6c5)cc1c4c23

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
HCRTR1 O43613 1/20 0.30
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849649 0.96 LPL (0.33) LPLLIPG
SCHEMBL17849640 0.87 LPL (0.36) LPLLIPGCHRNA1CHRNGCHRNB1
SCHEMBL17849634 0.86
SCHEMBL15909660 0.85
SCHEMBL17849633 0.85 LPL (0.35) LPLLIPGCHRNA1CHRNGCHRNB1
SCHEMBL23180789 0.84 HCRTR1 (0.33) LPLLIPGHCRTR1CHRNA1CHRNG
SCHEMBL24841786 0.84 HCRTR1 (0.33) LPLLIPGHCRTR1CHRNA1CHRNG
SCHEMBL18680170 0.84 MMP12 (0.32) HCRTR1MMP12MMP13
SCHEMBL13888800 0.84 LPL (0.34) LPLLIPG
SCHEMBL17849636 0.84 LPL (0.36) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed