SCHEMBL17849686

SCHEMBL17849686

c1ccc(-c2ccc(N(c3ccc(-c4cc5c6c(ccc7cccc(c76)C5(c5ccccc5)c5ccccc5)c4)cc3)c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSPO P30536 1/20 0.33
PTGES O14684 1/20 0.32
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849624 0.90 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL17849685 0.88 TSPO (0.35) KDM4EATML3MBTL1TSPOPTGES
SCHEMBL13030191 0.87 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOPTGES
SCHEMBL23180823 0.85 KDM4E (0.32) KDM4EATML3MBTL1TSPO
SCHEMBL24842053 0.85 KDM4E (0.32) KDM4EATML3MBTL1TSPO
SCHEMBL18803244 0.84 KDM4E (0.34) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17849609 0.84 KDM4E (0.34) KDM4EATML3MBTL1TSPOPTGES
SCHEMBL13030201 0.84 KDM4E (0.43) KDM4EATML3MBTL1TSPOPTGES
SCHEMBL24841606 0.84 TSPO (0.31) KDM4EATML3MBTL1TSPO
SCHEMBL20435192 0.84 PTGES (0.32) KDM4EATML3MBTL1TSPOPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed