Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850325 | 0.92 | LMNA (0.48) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL17850326 | 0.84 | PTPN1 (0.49) | KMT2APOLBMEN1USP2PTPN1 | |
| SCHEMBL13250764 | 0.82 | LMNA (0.57) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL15592369 | 0.82 | LMNA (0.57) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL13447781 | 0.82 | LMNA (0.57) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL17850294 | 0.82 | LMNA (0.57) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL17850343 | 0.82 | LMNA (0.57) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL22022411 | 0.78 | USP2 (0.48) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL14437199 | 0.78 | LMNA (0.59) | KMT2APOLBMEN1USP2LMNA | |
| SCHEMBL5321405 | 0.78 | LMNA (0.59) | KMT2APOLBMEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034510-A1 | OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE | Alnylam Pharmaceuticals Inc. (US) | 2016-06-22 | — | — | EP | disclosed |