Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850422 | 0.90 | MET (0.39) | MEN1KMT2APOLBGAAIDO1 | |
| SCHEMBL10194740 | 0.83 | GAA (0.39) | POLBGAAIDO1TDO2KDM4E | |
| SCHEMBL17850442 | 0.82 | MET (0.39) | MEN1KMT2APOLBCNR2KDM4E | |
| SCHEMBL10194759 | 0.80 | JAK2 (0.40) | GAAIDO1TDO2ALDH1A1KDM4E | |
| SCHEMBL17850389 | 0.74 | MET (0.44) | IDO1TDO2ALDH1A1METSMN1; SMN2 | |
| SCHEMBL10194916 | 0.73 | IDO1 (0.42) | MEN1KMT2AGAAIDO1TDO2 | |
| SCHEMBL10194694 | 0.71 | MET (0.42) | GAAIDO1TDO2ALDH1A1KDM4E | |
| SCHEMBL10194788 | 0.71 | JAK2 (0.42) | POLBGAAIDO1TDO2KDM4E | |
| SCHEMBL10194761 | 0.70 | MET (0.39) | GAAIDO1TDO2ALDH1A1KDM4E | |
| SCHEMBL17850414 | 0.69 | HPGD (0.40) | GAAIDO1TDO2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |